Allopurinol, furosemide and a phytotherapeutic agent (Bazoton uno) reverse P-glycoprotein-mediated doxorubicin resistance in human uterine sarcoma MES-SA/Dx5 cells: a novel therapeutic perspective

J Biol Regul Homeost Agents. 2019;33(3):991-997.

Authors

A Angelini^{1

2}, M A Centurione³, R Di Pietro¹, L Centurione¹

Affiliations

¹ Department of Medicine and Aging Science, School of Medicine and Health Science University of Chieti-Pescara, Italy.
² Research Center on Aging and Translational Medicine (Ce.S.I. Met), "G. D'Annunzio" University of Chieti-Pescara, Italy.
³ Institute of Molecular Genetics, National Research Council, Unit of Chieti, Italy.

PMID: 31162035

No abstract available

Keywords: Bazoton uno; MDR; MES-SA/Dx5 cells; P-glycoprotein; allopurinol; furosemide.

Publication types

Letter

MeSH terms

ATP Binding Cassette Transporter, Subfamily B, Member 1
Allopurinol / pharmacology*
Cell Line, Tumor
Doxorubicin
Drug Resistance, Neoplasm*
Female
Furosemide / pharmacology*
Humans
Plant Extracts / pharmacology*
Sarcoma / drug therapy
Sarcoma / pathology*
Uterine Neoplasms / drug therapy
Uterine Neoplasms / pathology*

Substances

ATP Binding Cassette Transporter, Subfamily B, Member 1
Plant Extracts
Allopurinol
Furosemide
Doxorubicin
Bazoton