Post-transplant Lupus Nephritis Recurrence: A Case Report and Review of the Literature

Abstract

Despite progress in treating lupus nephritis, the incidence of end-stage chronic kidney disease has increased. Renal transplantation is the treatment of choice for these patients and has been successfully performed on systemic lupus erythematosus (SLE) since 1959. The main concern in these patients is post-transplant lupus nephritis recurrence. Several questions remain for SLE patients following transplantation, including fear of lupus nephritis recurrence, choice of immunosuppressive therapy, and how to manage the disease and associated complications to reduce morbidity and risk of death.