Tissue engineering of skin is a field with high research activities and major importance for wound healing, especially following burn injuries. Animal models enable to test tissue-engineered skin as well as different types of cells in a realistic setting. Although there are several challenges in working with pigs, it is a good model because of its similarity to the human skin and a comparable wound regeneration. Here, we explain our routinely used methods for using pig models to test tissue-engineered skin in burn injuries.
Keywords: Burn injury; Pig model; Skin graft; Tissue engineering; Wound healing.