First report of linezolid-resistant cfr-positive methicillin-resistant Staphylococcus aureus in humans in Portugal

Vanessa Silva; Francisco Almeida; Adriana Silva; Susana Correia; José António Carvalho; Ana Paula Castro; Eugénia Ferreira; Vera Manageiro; Manuela Caniça; Gilberto Igrejas; Patrícia Poeta

doi:10.1016/j.jgar.2019.05.017

First report of linezolid-resistant cfr-positive methicillin-resistant Staphylococcus aureus in humans in Portugal

J Glob Antimicrob Resist. 2019 Jun:17:323-325. doi: 10.1016/j.jgar.2019.05.017. Epub 2019 May 22.

Authors

Affiliations

¹ MicroART - Microbiology and Antibiotic Resistance Team, Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal; Department of Genetics and Biotechnology, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal; Functional Genomics and Proteomics Unit, University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal; Associated Laboratory for Green Chemistry (LAQV-REQUIMTE), University NOVA of Lisboa, Lisboa, Caparica, Portugal.
² Department of Genetics and Biotechnology, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal.
³ MicroART - Microbiology and Antibiotic Resistance Team, Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal; Department of Genetics and Biotechnology, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal; Functional Genomics and Proteomics Unit, University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal.
⁴ Centro Hospitalar de Trás-os-Montes e Alto Douro E.P.E., Vila Real, Portugal.
⁵ National Reference Laboratory of Antibiotic Resistances and Healthcare Associated Infections (NRL-AMR/HAI), Department of Infectious Diseases, National Institute of Health Dr Ricardo Jorge, Av. Padre Cruz, 1649-016, Lisbon, Portugal; Centre for the Studies of Animal Science, Institute of Agrarian and Agri-Food Sciences and Technologies, Oporto University, Oporto, Portugal.
⁶ Department of Genetics and Biotechnology, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal; Functional Genomics and Proteomics Unit, University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal; Associated Laboratory for Green Chemistry (LAQV-REQUIMTE), University NOVA of Lisboa, Lisboa, Caparica, Portugal.
⁷ MicroART - Microbiology and Antibiotic Resistance Team, Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal; Associated Laboratory for Green Chemistry (LAQV-REQUIMTE), University NOVA of Lisboa, Lisboa, Caparica, Portugal. Electronic address: ppoeta@utad.pt.

PMID: 31125626
DOI: 10.1016/j.jgar.2019.05.017

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology
Bacterial Proteins / genetics*
Drug Resistance, Multiple, Bacterial / drug effects*
Drug Resistance, Multiple, Bacterial / genetics
Humans
Linezolid / pharmacology*
Methicillin-Resistant Staphylococcus aureus / drug effects*
Methicillin-Resistant Staphylococcus aureus / genetics
Methicillin-Resistant Staphylococcus aureus / isolation & purification
Microbial Sensitivity Tests
Multilocus Sequence Typing
Portugal
Staphylococcal Infections / microbiology*

Substances

Anti-Bacterial Agents
Bacterial Proteins
CFR protein, Staphylococcus aureus
Linezolid