The Impact of Melt Electrowritten Scaffold Design on Porosity Determined by X-Ray Microtomography

Tissue Eng Part C Methods. 2019 Jun;25(6):367-379. doi: 10.1089/ten.TEC.2018.0373.

Abstract

Melt electrowriting is an AM technology that bridges the gap between solution electrospinning and melt microextrusion technologies. It can be applied to biomaterials and tissue engineering by making a spectrum of scaffolds with various laydown patterns at dimensions not previously studied. Using submicrometer X-ray tomography, a "fingerprint" of porosity for such scaffolds can be obtained and used as an important measure for quality control, to ensure that the scaffold fabricated is the one designed and allows the selection of specific scaffolds based on desired porosities.

Keywords: biomaterials; electrospinning; medical devices; poly(ɛ-caprolactone); quality assurance; tissue engineering.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Electrochemistry / methods*
  • Equipment Design
  • Image Processing, Computer-Assisted
  • Porosity
  • Tissue Scaffolds / chemistry*
  • X-Ray Microtomography*