Base Editing: Efficient Installation of Point Mutations with Minimal Byproducts

Stem Cells Dev. 2019 Jun 1;28(11):712-713. doi: 10.1089/scd.2019.0080. Epub 2019 May 20.

Author

Gregory A Newby^{1

2

3}

Affiliations

¹ 1 Laboratory of David Liu, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts.
² 2 Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts.
³ 3 Merkin Institute of Transformative Technologies in Health Care, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.

PMID: 31107171
DOI: 10.1089/scd.2019.0080

No abstract available

Publication types

Letter

MeSH terms

CRISPR-Cas Systems / genetics*
Gene Editing / methods*
Genetic Therapy / methods*
Hematologic Diseases / therapy
Humans
Polymorphism, Single Nucleotide / genetics