Effect of early enteral nutrition in elderly patients with hip fracture during the perioperative period

J Back Musculoskelet Rehabil. 2020;33(1):109-117. doi: 10.3233/BMR-181191.

Abstract

Objective: This study aimed to assess the effects of early enteral nutrition (EN) in elderly patients with hip fracture.

Methods: The patients were classified into two groups (with and without EN). We compared the pre- and postoperative albumin (ALB) and inflammatory marker levels of each group and the time spent in bed and quality of life 3 months after surgery between the two groups.

Results: The pre- and postoperative IL-6 levels of the experimental group (61.68 ± 51.80 pg/L) were lower than those of the control group (233.11 ± 206.31 pg/L) (P< 0.001). The experimental group spent a shorter period of time in bed (38.75 ± 14.26 days) in comparison to the control group (99.71 ± 56.87 days) (P< 0.001). Quality of life was better in the experimental group than in the control group (P< 0.001).

Conclusions: Early EN reduced the increment of postoperative IL-6 levels and improved healing postoperatively.

Keywords: ALB; Hip fracture; inflamatory cytokines; inflamatory markers.

MeSH terms

  • Aged
  • Biomarkers / blood
  • Enteral Nutrition*
  • Female
  • Fracture Fixation / rehabilitation*
  • Hip Fractures / surgery*
  • Humans
  • Interleukin-6 / blood
  • Male
  • Middle Aged
  • Postoperative Period
  • Quality of Life*

Substances

  • Biomarkers
  • Interleukin-6