A concise review on drug-loaded electrospun nanofibres as promising wound dressings

J Med Eng Technol. 2019 Jan;43(1):38-47. doi: 10.1080/03091902.2019.1606950. Epub 2019 May 15.

Abstract

The diversity of wound types has gathered momentum to develop a wide range of wound dressings to improve different aspects of the wound healing process. Wound healing is a dynamic, complex and highly regulated mechanism of tissue repair and regeneration. The wound dressing should encourage regeneration and prevent possible infection or scaring. Wound dressings are different from the bandages as they come in direct contact with the wound and are used to absorb exudates and accelerate healing. Wound dressings can have a variety of functions, depending upon the type, severity, and position of the wound. In this review, we have studied the properties of nanofibrous wound dresses and possible approaches to load biological components into them for wound healing improvement.

Keywords: Wound healing; biomaterials; drug loading; electrospinning; wound dressing.

Publication types

  • Review

MeSH terms

  • Bandages*
  • Drug Delivery Systems*
  • Humans
  • Nanofibers*
  • Wound Healing