1 Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
2 Quantitative Systems Pharmacology, Early Clinical Development, Pfizer Inc, Cambridge, Massachusetts, USA.
3 Division of Neuroscience, National Institute on Aging at the National Institutes of Health, Bethesda, Maryland, USA.
4 Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
5 Bill & Melinda Gates Foundation, Seattle, Washington, USA.