Biochemistry, Immunoglobulin E

Excerpt

Immunoglobulin E is 1 of the 5 classes of immunoglobulins (IgM, IgG, IgD, IgA, IgE). IgE has a unique chemical structure and various physiological functions, such as type I hypersensitivity reactions, parasitic infections, autoimmune processes, and venom protection. It was the last of the immunoglobulin family to be discovered. Since then, it has spurred vast research to characterize its biochemistry and role in disease processes. Technological advancements have also been used to evaluate patient IgE levels and new pharmacological therapies that may inhibit its function altogether. The following article aims to provide an overview detailing the biochemical structure and function of IgE, as well as some examples of its clinical implications.