All Roads Lead to Rome: Hippocampal Stem Cells Hop(x) the Continuous Way

Qing-Ran Bai; Qin Shen

doi:10.1016/j.stem.2019.04.013

All Roads Lead to Rome: Hippocampal Stem Cells Hop(x) the Continuous Way

Cell Stem Cell. 2019 May 2;24(5):683-684. doi: 10.1016/j.stem.2019.04.013.

Authors

Qing-Ran Bai¹, Qin Shen²

Affiliations

¹ Tongji Hospital, Brain and Spinal Cord Innovative Research Center, School of Life Sciences and Technology, Tongji University, Shanghai, China; Frontier Science Research Center for Stem Cells, Ministry of Education, China.
² Tongji Hospital, Brain and Spinal Cord Innovative Research Center, School of Life Sciences and Technology, Tongji University, Shanghai, China; Frontier Science Research Center for Stem Cells, Ministry of Education, China. Electronic address: shenqin@tongji.edu.cn.

PMID: 31051131
DOI: 10.1016/j.stem.2019.04.013

Abstract

Recently in Cell, Berg et al. (2019) show that Hopx-expressing neural progenitor cells in the embryonic dentate gyrus contribute to dentate neurogenesis through the embryonic to adult stage, exhibiting a common transcriptomic and epigenomic signature and developmental dynamics. This finding suggests a continuous model for neurogenesis in the dentate gyrus.

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MeSH terms

Dentate Gyrus
Hippocampus
Neural Stem Cells*
Neurogenesis*