Background: Spindle cell hemangioma (SCH) was an extremely rare benign tumor which typically arised in the subcutis of the distal extremities of young people. In this study, we reported a case of multiple spindle cell hemangioma in both lungs.
Case presentation: A 19-year-old HIV-negative female was found to have multiple lung nodules by the chest X-ray during the physical examination. Her chest CT scan revealed multiple round-like pulmonary nodules in both lungs. Based on the morphological features and immunohistochemical examination for vascular markers CD31, CD34 and D2-40, the mass was diagnosed as SCH after surgery.
Conclusion: SCH was an extremely rare tumor especially in both lungs. It should be considered in differential diagnosis of multiple lung nodules. Pathological features, the expression of CD31, CD34 and D2-40 could help to diagnosis of SCH.
Keywords: Hemangioma of lung; Multiple nodules of lung; Spindle cell hemangiomas.