Therapeutic plasma exchange in nephrology. Where it applies?

Eric Alamartine; Nicolas Maillard

doi:10.1016/j.transci.2019.04.010

Therapeutic plasma exchange in nephrology. Where it applies?

Transfus Apher Sci. 2019 Jun;58(3):262-265. doi: 10.1016/j.transci.2019.04.010. Epub 2019 Apr 19.

Authors

Eric Alamartine¹, Nicolas Maillard²

Affiliations

¹ Service de Néphrologie Dialyse Transplantation Rénale, CHU Saint Etienne, GIMAP EA3064, Université Jean Monnet, Saint Etienne Lyon, France. Electronic address: eric.alamartine@chuse.fr.
² Service de Néphrologie Dialyse Transplantation Rénale, CHU Saint Etienne, GIMAP EA3064, Université Jean Monnet, Saint Etienne Lyon, France. Electronic address: nicolas.maillard@chu-st-etienne.fr.

PMID: 31029612
DOI: 10.1016/j.transci.2019.04.010

Abstract

Plasma exchange had been proposed to treat many kidney diseases. A few controlled studies, observational studies, and mechanistic evidence have specified the better indications, which are thrombotic microangiopathies, kidney transplantation and ANCA-associated vasculitides. Plasma removal can be realized by filtration, centrifugation, or immunoadsorption, with differences in efficacy, but these also impact on volume load and anticoagulation in patients with renal failure.

Keywords: Immunoadsorp; Kidney diseases; Plasma exchange; tion.

Publication types

Review

MeSH terms

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / therapy*
Humans
Kidney Diseases / therapy*
Plasma Exchange*
Thrombotic Microangiopathies / therapy*