Exome sequencing and pathogenicity-network analysis of five French families implicate mTOR signalling and autophagy in familial sarcoidosis

Eur Respir J. 2019 Aug 1;54(2):1900430. doi: 10.1183/13993003.00430-2019. Print 2019 Aug.

¹ Dept of Molecular and Medical Genetics, Hospices Civils de Lyon, University Hospital, Bron, France alain.calender@chu-lyon.fr.
² Inflammation and Immunity of the Respiratory Epithelium, Lyon 1 Claude Bernard University, EA-7426 (PI3), Pierre-Bénite, France.
³ These authors contributed equally to this work.
⁴ Center for Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
⁵ Dept of Molecular and Medical Genetics, Hospices Civils de Lyon, University Hospital, Bron, France.
⁶ Lung and Hypoxia, EA-2363, University Sorbonne Paris Cité, Paris, France.
⁷ Dept of Biostatistics and Bioinformatics, Hospices Civils de Lyon, University Hospital, Lyon, France.
⁸ University Lyon 1, CNRS, Laboratory of Biometry and Evolutionary Biology, UMR 5558, Villeurbanne, France.
⁹ Dept of Pulmonology, Hospices Civils de Lyon, Louis Pradel Hospital, Lyon, France.
¹⁰ Dept of Pulmonology, Hospices Civils de Lyon, Croix Rousse Hospital, Lyon, France.
¹¹ Cancer Research Center, INSERM U-1052, CNRS-5286, Lyon, France.
¹² Dept of Pulmonology, Avicenne Hospital, EA-2363, University Paris 13, Bobigny, France.
¹³ Dept of Pulmonology, European Hospital Georges Pompidou, Paris, France.
¹⁴ INSERM U-1272, University Paris 13 and AP-HP, Avicenne Hospital, Bobigny, France.

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