Technology for Augmenting Type 1 Diabetes Mellitus Management

J Pediatr Pharmacol Ther. 2019 Mar-Apr;24(2):99-106. doi: 10.5863/1551-6776-24.2.99.

Abstract

Type 1 diabetes mellitus has witnessed significant progress in its management over the past several decades. This review highlights technologic advancements in type 1 diabetes management. Continuous glucose monitoring systems are now available at various functionality and cost levels, addressing diverse patient needs, including a recently US Food and Drug Administration (FDA)-approved implantable continuous glucose monitoring system (CGMS). Another dimension to these state-of-the-art technologies is CGMS and insulin pump integration. These integrations have allowed for CGMS-based adjustments to basal insulin delivery rates and suspension of insulin delivery when a low blood glucose event is predicted. This review also includes a brief discussion of upcoming technologies such as patch-based CGMS and insulin-glucagon dual-hormonal delivery.

Keywords: continuous glucose monitoring; continuous subcutaneous infusion; glucagon; insulin; insulin infusion system; type 1 diabetes mellitus.

Publication types

  • Review