Repetitive transcranial magnetic stimulation in non-treatment-resistant depression

Br J Psychiatry. 2019 Aug;215(2):445-446. doi: 10.1192/bjp.2019.75. Epub 2019 Apr 24.

Abstract

Repetitive transcranial magnetic stimulation (rTMS) has been investigated as treatment for major depressive episodes since the early 1990s. Using data from a recent meta-analysis, we show that most patients included in randomised trials display relatively high degrees of treatment resistance. This might have unfavourably biased the clinical reputation of rTMS.Declaration of interestsM.K. has received a lecture fee from Innomed Medizintechnik in 2017 and 2018.

Keywords: Transcranial magnetic stimulation; depression; medication-naive; rTMS; treatment resistance.

Publication types

  • Editorial

MeSH terms

  • Depressive Disorder, Major / therapy*
  • Depressive Disorder, Treatment-Resistant / therapy*
  • Humans
  • Transcranial Magnetic Stimulation*
  • Treatment Outcome