Nipah Virus Sequences from Humans and Bats during Nipah Outbreak, Kerala, India, 2018

Pragya D Yadav; Anita M Shete; G Arun Kumar; Prasad Sarkale; Rima R Sahay; Chandni Radhakrishnan; Rajen Lakra; Prachi Pardeshi; Nivedita Gupta; Raman R Gangakhedkar; V R Rajendran; Rajeev Sadanandan; Devendra T Mourya

doi:10.3201/eid2505.181076

Nipah Virus Sequences from Humans and Bats during Nipah Outbreak, Kerala, India, 2018

Emerg Infect Dis. 2019 May;25(5):1003-1006. doi: 10.3201/eid2505.181076.

Authors

Pragya D Yadav, Anita M Shete, G Arun Kumar, Prasad Sarkale, Rima R Sahay, Chandni Radhakrishnan, Rajen Lakra, Prachi Pardeshi, Nivedita Gupta, Raman R Gangakhedkar, V R Rajendran, Rajeev Sadanandan, Devendra T Mourya

Abstract

We retrieved Nipah virus (NiV) sequences from 4 human and 3 fruit bat (Pteropus medius) samples from a 2018 outbreak in Kerala, India. Phylogenetic analysis demonstrated that NiV from humans was 96.15% similar to a Bangladesh strain but 99.7%-100% similar to virus from Pteropus spp. bats, indicating bats were the source of the outbreak.

Keywords: Human; India; Kerala; Nipah virus; Pteropus medius; next-generation sequencing; qRT-PCR; viruses.

Publication types

Historical Article
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cells, Cultured
Chiroptera / virology*
Cytopathogenic Effect, Viral
Disease Outbreaks*
Henipavirus Infections / epidemiology*
Henipavirus Infections / history
Henipavirus Infections / transmission
Henipavirus Infections / virology*
History, 21st Century
Humans
India / epidemiology
Mutation
Nipah Virus / classification*
Nipah Virus / genetics*
Public Health Surveillance