Integrated Printed Microfluidic Biosensors

Jacky F C Loo; Aaron H P Ho; Anthony P F Turner; Wing Cheung Mak

doi:10.1016/j.tibtech.2019.03.009

Integrated Printed Microfluidic Biosensors

Trends Biotechnol. 2019 Oct;37(10):1104-1120. doi: 10.1016/j.tibtech.2019.03.009. Epub 2019 Apr 13.

Authors

Jacky F C Loo¹, Aaron H P Ho¹, Anthony P F Turner², Wing Cheung Mak³

Affiliations

¹ Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong Special Administrative Region.
² SATM, Cranfield University, Cranfield, MK430AL, UK. Electronic address: a.p.turner@cranfield.ac.uk.
³ Biosensors and Bioelectronics Centre, Department of Physics, Chemistry and Biology (IFM), Linköping University, 58183, Linköping, Sweden. Electronic address: wing.cheung.mak@liu.se.

PMID: 30992149
DOI: 10.1016/j.tibtech.2019.03.009

Abstract

Integrated printed microfluidic biosensors are one of the most recent point-of-care (POC) sensor developments. Fast turnaround time for production and ease of customization, enabled by the integration of recognition elements and transducers, are key for on-site biosensing for both healthcare and industry and for speeding up translation to real-life applications. Here, we provide an overview of recent progress in printed microfluidics, from the 2D to the 4D level, accompanied by novel sensing element integration. We also explore the latest trends in integrated printed microfluidics for healthcare, especially POC diagnostics, and food safety applications.

Keywords: biosensors; just-in-time production; point-of-care diagnosis; printed microfluidics; processable materials; sample-to-answer.

Publication types

Review

MeSH terms

Biosensing Techniques / instrumentation*
Equipment Design
Food Safety
Lab-On-A-Chip Devices*
Molecular Diagnostic Techniques / instrumentation*
Printing, Three-Dimensional*
Transducers