Bullous pemphigoid with dipeptidyl peptidase-4 inhibitors: Clinical features and pathophysiology

J Diabetes Investig. 2019 Sep;10(5):1168-1170. doi: 10.1111/jdi.13060. Epub 2019 May 14.

Abstract

It is strongly suggested that dipeptidyl peptidase-4 inhibitors are associated with increased risk of bullous pemphigoid onset, especially in the elderly. Heightened clinical vigilance for bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitor use is required in daily diabetes care.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Dipeptidyl-Peptidase IV Inhibitors / adverse effects*
  • Humans
  • Male
  • Pemphigoid, Bullous / chemically induced
  • Pemphigoid, Bullous / pathology*
  • Pemphigoid, Bullous / prevention & control
  • Prognosis
  • Withholding Treatment

Substances

  • Dipeptidyl-Peptidase IV Inhibitors