Asymptomatic Prostate Cancer Brain Metastases on 68Ga-PSMA PET/CT

Clin Nucl Med. 2019 Jun;44(6):e382-e384. doi: 10.1097/RLU.0000000000002548.

Abstract

Brain metastases from prostate cancer are rare and occur at a late stage in the natural history of the disease. Men usually present with neurological manifestations. We present a 66-year-old asymptomatic man who had incidental brain metastases detected on Ga-PSMA PET/CT, which was later confirmed on biopsy to be prostate adenocarcinoma. With newer androgen deprivation agents and improved imaging capabilities increasing the mean survival and thus the incidence of brain metastases from prostate cancer, it is important to consider this important differential not only in men who display neurological symptoms but also in men who are asymptomatic.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Asymptomatic Diseases*
  • Brain Neoplasms / diagnostic imaging*
  • Brain Neoplasms / secondary*
  • Gallium Isotopes
  • Gallium Radioisotopes
  • Humans
  • Male
  • Membrane Glycoproteins*
  • Organometallic Compounds*
  • Positron Emission Tomography Computed Tomography*
  • Prostatic Neoplasms / pathology*

Substances

  • Gallium Isotopes
  • Gallium Radioisotopes
  • Membrane Glycoproteins
  • Organometallic Compounds
  • gallium 68 PSMA-11