A 2-Year-Old Filly With Hereditary Equine Regional Dermal Asthenia: The First Case Report From China

Jing Li 李靖; Bo Liu; Feng Yu; Tianlong Liu; Yushi Peng; Yunhe Fu

doi:10.1016/j.jevs.2018.01.010

A 2-Year-Old Filly With Hereditary Equine Regional Dermal Asthenia: The First Case Report From China

J Equine Vet Sci. 2018 May:64:1-4. doi: 10.1016/j.jevs.2018.01.010. Epub 2018 Feb 9.

Authors

Jing Li 李靖¹, Bo Liu², Feng Yu³, Tianlong Liu², Yushi Peng², Yunhe Fu⁴

Affiliations

¹ Department of Clinical Sciences, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China. Electronic address: jlivet@hotmail.com.
² Department of Clinical Sciences, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
³ Class of 2020, School of Veterinary Medicine, University of California, Davis, Davis, CA.
⁴ Department of Clinical Sciences, College of Veterinary Medicine, Jilin University, Changchun, People's Republic of China.

PMID: 30973143
DOI: 10.1016/j.jevs.2018.01.010

Abstract

Hereditary equine regional dermal asthenia (HERDA) is an autosomal recessive inheritable disorder described in the Quarter Horses and related breeds. In this case report, a 2-year-old Quarter Horse filly was diagnosed with HERDA based on clinical findings and genetic testing. The observed clinical signs were stretchy, loose and thin skin, and open wounds on the upper body. Skin biopsy results were consistent with the common findings previously described in the literature. This is the first HERDA case report in China (and in Asia). Genetic testing protocols should be implemented for breeding farms to prevent the disease.

Keywords: China; Diagnosis; HERDA; Histopathology; Quarter horse.