Post-cholecystectomy syndrome (PCS) is the term used to describe the persistence of biliary colic or right upper quadrant abdominal pain with a variety of gastrointestinal symptoms, which are similar to the features experienced by an individual before cholecystectomy. As the name suggests, this syndrome can represent either a continuation of symptoms caused by gallbladder pathology or development of new symptoms that usually correlate with the gallbladder. The symptoms include fatty food intolerance, nausea, vomiting, heartburn, flatulence, indigestion, diarrhea, jaundice, and intermittent episodes of abdominal pain. Post-cholecystectomy syndrome can present early, typically in the post-operative period, but can also manifest months to years after surgery.
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