Wolffian tumor (female adnexal tumor of Wolffian origin) presenting as a pelvic side wall mass: Report of a case

Claire Rosen; Emily Reardon; Susan Shyu; Julia Terhune; Paul Saats; Olga Ioffe; Stephen Kavic

doi:10.1177/2050313X19839534

Wolffian tumor (female adnexal tumor of Wolffian origin) presenting as a pelvic side wall mass: Report of a case

SAGE Open Med Case Rep. 2019 Apr 1:7:2050313X19839534. doi: 10.1177/2050313X19839534. eCollection 2019.

Authors

Claire Rosen¹, Emily Reardon¹, Susan Shyu², Julia Terhune¹, Paul Saats², Olga Ioffe², Stephen Kavic¹

Affiliations

¹ Department of Surgery, University of Maryland Medical Center, Baltimore, MD, USA.
² Department of Pathology, University of Maryland Medical Center, Baltimore, MD, USA.

Abstract

The Wolffian tumor, previously identified as "female adnexal tumor of probable Wolffian origin," is a rare tumor first described in 1973. The tumor is usually benign and is characterized by diffuse and tubular patterns, accentuated by reticulum and periodic acid-Schiff stains. Immunohistochemistry is used to further identify and classify these tumors, which are positive for cytokeratins, vimentin, inhibin, calretinin, and CD10 and negative for cytokeratin 20, epithelial membrane antigen, estrogen receptor, progesterone receptor, 34betaE12, and glutathione S-transferase. We report the case of a 47-year-old female with Wolffian tumor arising from the pelvic sidewall, separate from all reproductive organs. This is the first reported case of Wolffian tumor in this location.

Keywords: Wolffian; adnexal tumor; female adnexal tumor of probable Wolffian origin; immunohistochemistry; reproduction.

Publication types

Case Reports