Comparison of 2 Surgeries in Correction of Severe Kyphotic Deformity Caused by Ankylosing Spondylitis: Vertebral Column Decancellation and Pedicle Subtraction Osteotomy

World Neurosurg. 2019 Jul:127:e972-e978. doi: 10.1016/j.wneu.2019.04.011. Epub 2019 Apr 6.

Abstract

Objective: To compare the treatment results between 1-level vertebral column decancellation (VCD) and pedicle subtraction osteotomy (PSO) for correcting severe kyphotic deformity in ankylosing spondylitis (AS). VCD and PSO have been used to correct AS-related kyphotic deformity, but the differences on correcting results between VCD and PSO are not clear.

Methods: Between 2013 and 2015, 57 patients underwent 1-level spinal osteotomy (VCD: n = 30; PSO: n = 27) for correcting kyphotic deformity. Sagittal parameters, fusion results, surgical information, and clinical outcomes were documented and compared. All data were obtained before and 1 week after surgery, 6 months after surgery, and at final follow-up (at least 2 years).

Results: VCD provided significantly greater osteotomy angle (50.8° ± 9.7°) than PSO (38.5° ± 6.1°). In the VCD group, the change of the anterior column was 5.0 ± 1.3 mm, which was larger than the PSO group. The middle column was shortened by 9.9 ± 2.0 mm and 19.1 ± 3.3 mm in the VCD group and PSO group, respectively. There was no significant difference in operating time and blood loss between the 2 groups. All cases had solid fusion. Between the 2 groups, Scoliosis Research Society Outcomes Instrument-22 scores were similar at the final follow-up. No major acute complications occurred in both groups.

Conclusions: VCD is a safe and effective method in treating rigid kyphotic deformity secondary to AS. VCD provides a larger correction angle in one segment and preserves more height of osteotomized vertebrae than PSO.

Keywords: Ankylosing spondylitis; Deformity; Osteotomy; Pedicle subtraction osteotomy; Thoracolumbar kyphosis; Vertebral column decancellation.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Female
  • Follow-Up Studies
  • Humans
  • Kyphosis / diagnostic imaging*
  • Kyphosis / etiology
  • Kyphosis / surgery*
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / surgery
  • Male
  • Middle Aged
  • Osteotomy / methods*
  • Osteotomy / standards
  • Retrospective Studies
  • Severity of Illness Index
  • Spinal Fusion / methods*
  • Spinal Fusion / standards
  • Spondylitis, Ankylosing / complications
  • Spondylitis, Ankylosing / diagnostic imaging*
  • Spondylitis, Ankylosing / surgery*
  • Thoracic Vertebrae / diagnostic imaging
  • Thoracic Vertebrae / surgery
  • Treatment Outcome