[FUNCTIONAL STATUS OF THE VISUAL ORGAN DURING PREECLAMPSIA]

Georgian Med News. 2019 Feb:(287):39-44.
[Article in Russian]

Abstract

The purpose of this research is to study the effect of preeclampsia of pregnant women on the functional status of the visual organ. The research study was made on 77 pregnant women (154 eyes) from 17 to 43 years old. Based on the analysis of the research results, during uncomplicated pregnancy and mild preeclampsia we found no significant changes in the foveolar retinal thickness and macular retinal volume both during various trimesters of pregnancy and postpartum. In moderate preeclampsia along with spasm of retinal arterioles and congestion in the venous bed in the third trimester, there was a statistically significant increase in the average thickness of the foveolar retina (183.8±4.2 micron versus 158.6±4.4 and 157.8±4.1 micron respectively in the control and in the comparison group, p<0.05); 57% of the eyes have a significant increase of the average FRT data (7.38±0.05 mm³ versus 7.01±0.02 mm³ in the comparison and control groups, p<0.05); in one case, the macula oedema was determined by ophthalmoscopy. In this group, the highest increase of the foveal retina thickness and the increase of the macular retina volume (198.3±4.5 micron, and 7.90±0.07 mm³, p<0.05) were observed. After 2-4 months postpartum in the subgroups of moderate and severe preeclampsia, there was a reduction in the average values of foveal retinal thickness and macular retinal volume, although the mean MRV values still significantly exceeded the baseline, and in 10 eyes FRT elevated remained indices. Changes in the retina morphometric parameters directly correlated with the severity of preeclampsia. Identified changes in the macular retina must be considered when predicting the risk of the macular pathology formation many years postpartum.

MeSH terms

  • Adolescent
  • Adult
  • Female
  • Humans
  • Macular Edema / physiopathology
  • Pre-Eclampsia / pathology*
  • Pregnancy
  • Retina / anatomy & histology*
  • Retina / physiology*
  • Tomography, Optical Coherence*
  • Young Adult