Non-HACEK Gram-negative bacillus endocarditis

M Ertugrul Mercan; F Arslan; S Ozyavuz Alp; A Atilla; D Seyman; G Guliyeva; B Kayaaslan; S Sari; B Mutay Suntur; B Isik; A Mert

doi:10.1016/j.medmal.2019.03.013

Non-HACEK Gram-negative bacillus endocarditis

Med Mal Infect. 2019 Nov;49(8):616-620. doi: 10.1016/j.medmal.2019.03.013. Epub 2019 Mar 30.

Authors

M Ertugrul Mercan¹, F Arslan², S Ozyavuz Alp³, A Atilla⁴, D Seyman⁵, G Guliyeva⁶, B Kayaaslan⁷, S Sari⁸, B Mutay Suntur⁹, B Isik¹⁰, A Mert¹¹

Affiliations

¹ Department of Cardiology, Faculty of Medicine, Istanbul Acibadem University, Istanbul, Turkey.
² Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey. Electronic address: ferhatarslandr@hotmail.com.
³ Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
⁴ Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.
⁵ Department of Infectious Diseases and Clinical Microbiology, Health Sciences University, Antalya Education and Training Hospital, Antalya, Turkey.
⁶ Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, İzmir, Turkey.
⁷ Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey.
⁸ Department of Intensive Care Unit, Health Sciences University, Turkiye Yüksek İhtisas Taining and Research Hospital, Ankara, Turkey.
⁹ Department of Infectious Disease and Clinical Microbiology, Health Sciences University, Adana Numune Taining and Research Hospital, Adana, Turkey.
¹⁰ Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.
¹¹ Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey.

PMID: 30940412
DOI: 10.1016/j.medmal.2019.03.013

Abstract

Patients and methods: Retrospective analysis of clinical data using 26 diagnosed non-HACEK Gram-negative infective endocarditis cases from nine hospitals in Turkey.

Results: Mean age of patients was 53 (28-84) years, with a 23% case fatality. Nineteen (73%) of the 26 patients had at least one predisposing factor. The presence of a central venous catheter was the most common predisposing factor (7/26 patients). Pseudomonasaeruginosa (7/26 patients) and Escherichiacoli (7/26 patients) were the most common pathogens. The median duration of the antibiotic therapy was 42 days (range 3-84 days). Surgical procedures were performed in 10 patients. The case fatality was similar in patients who did or did not undergo surgery (20% vs. 25%).

Keywords: Bactéries à Gram négatif; Catheterization; Cathétérisme; Endocardite; Endocarditis; Gram-negative bacteria.

Publication types

Multicenter Study

MeSH terms

Adult
Aged
Aged, 80 and over
Endocarditis, Bacterial / diagnosis
Endocarditis, Bacterial / microbiology*
Endocarditis, Bacterial / therapy
Female
Gram-Negative Bacterial Infections* / diagnosis
Gram-Negative Bacterial Infections* / therapy
Humans
Male
Middle Aged
Retrospective Studies