ZnSe:Fe2+ active laser crystal properties at different excitation wavelengths (2.94 and 4.1 μm) were investigated, and noticeable variations of the fluorescence spectra shape and their maxima positions, as well as changes in decay times, were observed. A stepwise shift of the laser oscillation wavelength from 4.7 μm at 2.94 μm pumping to 4.95 μm at 4.1 μm pumping was achieved at room temperature.