Thyrotoxicosis: Diagnosis and Management

Anu Sharma; Marius N Stan

doi:10.1016/j.mayocp.2018.10.011

Thyrotoxicosis: Diagnosis and Management

Mayo Clin Proc. 2019 Jun;94(6):1048-1064. doi: 10.1016/j.mayocp.2018.10.011. Epub 2019 Mar 25.

Authors

Anu Sharma¹, Marius N Stan²

Affiliations

¹ Division of Endocrinology, Metabolism and Diabetes, University of Utah School of Medicine, Salt Lake City, UT.
² Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN. Electronic address: stan.marius@mayo.edu.

PMID: 30922695
DOI: 10.1016/j.mayocp.2018.10.011

Abstract

Thyrotoxicosis is the clinical manifestation of excess thyroid hormone action at the tissue level due to inappropriately high circulating thyroid hormone concentrations. Hyperthyroidism, a subset of thyrotoxicosis, refers specifically to excess thyroid hormone synthesis and secretion by the thyroid gland. We performed a review of the literature on these topics utilizing published data in PubMed and MEDLINE. In this review, we discuss the more common etiologies of thyrotoxicosis, focusing on the current approach to diagnosis and management, new trends in those directions, and potential upcoming changes in the field.

Publication types

Review

MeSH terms

Adrenergic beta-Antagonists / therapeutic use*
Glucocorticoids / therapeutic use*
Humans
Propranolol / therapeutic use*
Thyroid Gland / surgery*
Thyrotoxicosis / diagnosis*
Thyrotoxicosis / drug therapy*

Substances

Adrenergic beta-Antagonists
Glucocorticoids
Propranolol