A Patient With Lung Adenocarcinoma With BRAF Gene Fusion and Response to Vemurafenib

Clin Lung Cancer. 2019 May;20(3):e224-e228. doi: 10.1016/j.cllc.2019.02.020. Epub 2019 Mar 4.
No abstract available

Keywords: Adenocarcinoma; BRAF; Lung; NGS; Rearrangement.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma of Lung / drug therapy
  • Adenocarcinoma of Lung / genetics*
  • Antineoplastic Agents / therapeutic use*
  • Carrier Proteins / genetics
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / genetics*
  • MAP Kinase Signaling System
  • Male
  • Middle Aged
  • Oncogene Proteins, Fusion / genetics*
  • Protein Kinase Inhibitors / therapeutic use*
  • Proto-Oncogene Proteins B-raf / genetics*
  • Remission Induction
  • Treatment Outcome
  • Vemurafenib / therapeutic use*

Substances

  • Antineoplastic Agents
  • Carrier Proteins
  • Oncogene Proteins, Fusion
  • Protein Kinase Inhibitors
  • TRIM24 protein, human
  • Vemurafenib
  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf