The Controlling Nutritional Status (CONUT) score is associated with prognosis in a variety of cancers, but the association with prognosis in oligometastatic prostate cancer has not been reported. And the effect of the CONUT score on the prognosis of prostate cancer was not compared with the platelet to lymphocyte ratio (PLR) and the neutrophil to lymphocyte ratio (NLR). A total of 94 patients who underwent surgery for oligometastatic prostate cancer from January 2015 to December 2017 were retrospectively analyzed.The appropriate cut-off values of CONUT, PLR, and NLR were determined by X-tail. CONUT scores were statistically significant for Gleason scores, T-stage, tumor margin, NLR, and PLR (P < 0.05). We evaluated the effect of CONUT scores on PSA progression-free survival. Univariate and multivariate analyses were performed to determine the independent predictors of CONUT scores. On univariate analysis, CONUT scores, NLR, and PLR were significantly associated with PSA progression-free survival (P < 0.05). Multivariate analysis showed that the CONUT score was an independent prognostic factor (P < 0.05). The present study indicates that the CONUT score is an independent prognostic factor for patients with oligometastatic prostate cancer.
Keywords: CONUT score; NLR; Oligometastasis; PLR; Prostate cancer.
Copyright © 2019 Elsevier Inc. All rights reserved.