PET/MR Imaging:: Current Updates on Pediatric Applications

Neha S Kwatra; Ruth Lim; Michael S Gee; Lisa J States; Arastoo Vossough; Edward Y Lee

doi:10.1016/j.mric.2019.01.012

PET/MR Imaging:: Current Updates on Pediatric Applications

Magn Reson Imaging Clin N Am. 2019 May;27(2):387-407. doi: 10.1016/j.mric.2019.01.012.

Authors

Neha S Kwatra¹, Ruth Lim², Michael S Gee², Lisa J States³, Arastoo Vossough³, Edward Y Lee⁴

Affiliations

¹ Department of Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: neha.kwatra@childrens.harvard.edu.
² Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
³ Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania, 324 South 34th Street, Philadelphia, PA 19104, USA.
⁴ Department of Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.

PMID: 30910104
DOI: 10.1016/j.mric.2019.01.012

Abstract

PET/MR imaging is an integrated imaging system that combines the high soft tissue resolution of MR imaging with the quantitative data obtained from PET into a single system. It is a relatively new imaging technique but with potential clinical use in pediatric oncologic and nononcologic processes in additional to its role in research. It is particularly relevant in pediatric patients due to reduced radiation burden compared with PET/CT and the ability to obtain exquisite functional and anatomic imaging in a single imaging session, thereby reducing the number of anesthesia/sedations. This review article focuses on the current as well as future applications of PET/MR imaging in pediatric imaging, including both oncologic and nononcologic indications.

Keywords: Attenuation correction; Functional imaging; Oncology; PET/MR imaging; Pediatrics; Radiation dose.

Publication types

Review

MeSH terms

Adolescent
Child
Child, Preschool
Humans
Magnetic Resonance Imaging / methods*
Multimodal Imaging / methods*
Pediatrics / methods*
Positron-Emission Tomography / methods*