Pancreatic cancer surgical management

Florence Jeune; Romain Coriat; Frédéric Prat; Bertrand Dousset; Jean-Christophe Vaillant; Sébastien Gaujoux

doi:10.1016/j.lpm.2019.02.027

Pancreatic cancer surgical management

Presse Med. 2019 Mar;48(3 Pt 2):e147-e158. doi: 10.1016/j.lpm.2019.02.027. Epub 2019 Mar 22.

Authors

Florence Jeune¹, Romain Coriat², Frédéric Prat², Bertrand Dousset³, Jean-Christophe Vaillant⁴, Sébastien Gaujoux³

Affiliations

¹ AP-HP, Pierre-and-Marie-Curie university, Paris VI, Pitié-Salpêtrière hospital, department of hepatobiliary surgery, pancreatic surgery and liver transplantation, 75651 Paris cedex, France. Electronic address: florence.jeune@hotmail.fr.
² AP-HP, Paris V, Paris Descartes faculty of medecine, Cochin hopsital, department of gastroenterology and oncology, 75014 Paris, France.
³ AP-HP, Paris V, Paris Descartes faculty of medicine, Cochin hospital, department of digestive, hepatobiliary and pancreatic surgery, 75014 Paris, France.
⁴ AP-HP, Pierre-and-Marie-Curie university, Paris VI, Pitié-Salpêtrière hospital, department of hepatobiliary surgery, pancreatic surgery and liver transplantation, 75651 Paris cedex, France.

PMID: 30905395
DOI: 10.1016/j.lpm.2019.02.027

Abstract

Pancreatic ductal adenocarcinoma (PDAC) remains a dismal prognosis and surgery is the only chance for cure. However, only few of the patients have localized tumor eligible for curative complete resection. Preoperative management and well-staging of the disease are the cornerstone for appropriate surgery and major issues to define the best therapeutic strategy. This review focuses on the surgical and optimal perioperative management of PDAC and summarizes updates data on the subject.

Publication types

Review

MeSH terms

Anastomosis, Surgical
CA-19-9 Antigen / blood
Carcinoma, Pancreatic Ductal / diagnostic imaging
Carcinoma, Pancreatic Ductal / surgery*
Clinical Decision-Making
Diagnostic Imaging
Drainage
Humans
Laparoscopy
Lymph Node Excision
Malnutrition / etiology
Malnutrition / therapy
Mesenteric Veins / surgery
Neoplasm Staging / methods
Nutritional Support
Pancreatectomy
Pancreatic Neoplasms / diagnostic imaging
Pancreatic Neoplasms / surgery*
Pancreaticoduodenectomy
Portal Vein / surgery
Postoperative Care
Preoperative Care

Substances

CA-19-9 Antigen