Axillary web syndrome: Incidence, pathogenesis, and management

Curr Probl Cancer. 2019 Dec;43(6):100470. doi: 10.1016/j.currproblcancer.2019.02.002. Epub 2019 Mar 15.

Abstract

Axillary web syndrome (AWS) refers to the development of fibrotic bands or "cords" in the axilla of patients who have undergone axillary lymph node dissection for breast cancer. We review the incidence, pathogenesis, risk factors, and management of AWS. AWS is a common complication in patients who undergo axillary lymph node dissection. Even though AWS is self-limited in most cases, it causes significant morbidity. The optimal management of AWS is unclear but physiotherapy appears to be beneficial. The widespread use of less invasive procedures to evaluate the presence of metastasis in the axillary lymph nodes (ie, sentinel lymph node biopsy) is expected to reduce the incidence of AWS. The close collaboration of surgeons, oncologists, and physiotherapists is necessary for the prevention and management of this frequent condition.

Keywords: Axillary lymph node dissection; Axillary web syndrome; Breast cancer; Physiotherapy.

Publication types

  • Review

MeSH terms

  • Axilla
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery*
  • Disease Management
  • Female
  • Humans
  • Incidence
  • Lymph Node Excision / adverse effects*
  • Lymphatic Diseases / epidemiology
  • Lymphatic Diseases / pathology
  • Lymphatic Diseases / therapy*
  • Syndrome