Domino Liver Transplantation: Where are we Now?

Abstract

Background: Domino transplant occurs when a recipient explanted graft is used for a second recipient.

Introduction: The first experience came from thoracic surgery by the observation that many patients during heart-lung transplantation actually showed a functional heart that could be employed in other subjects with a good result.

Results: This concept was then extended to the field of liver transplantation. At present, some patients transplanted for an inborn metabolic disease may be considered as excellent domino liver donors.

Conclusion: The results, limitations, clinical challenges and the donor and recipient features of domino liver transplantation are discussed in this manuscript.

Keywords: Amyloidosis transthyretin; domino; human; inborn disease; liver; transplantation..