Abstract
MPNSTs (malignant peripheral nerve sheath tumors) are a highly malignant group of soft tissue sarcomas and carry a very poor prognosis. Metastasis to bilateral adrenal glands is very rare in such group of neoplasms. We discuss a case of 85-year-old man who was diagnosed with MPNST from prevertebral mass with metastases to bilateral adrenal glands and bone marrow from the beginning and role of serial F-FDG PET/CT scans in response assessment first to sunitinib (tyrosine kinase inhibitor) and then to liposomal doxorubicin.
MeSH terms
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Adrenal Gland Neoplasms / diagnostic imaging*
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Adrenal Gland Neoplasms / secondary
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Aged, 80 and over
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Antineoplastic Agents / therapeutic use
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Doxorubicin / therapeutic use
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Fluorodeoxyglucose F18
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Humans
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Male
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Nerve Sheath Neoplasms / diagnostic imaging*
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Nerve Sheath Neoplasms / drug therapy
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Nerve Sheath Neoplasms / pathology
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Neurofibrosarcoma / diagnostic imaging*
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Neurofibrosarcoma / drug therapy
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Neurofibrosarcoma / pathology
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Positron Emission Tomography Computed Tomography*
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Radiopharmaceuticals
Substances
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Antineoplastic Agents
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Radiopharmaceuticals
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Fluorodeoxyglucose F18
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Doxorubicin