Image reconstruction utilizing median filtering applied to elastography

Biomed Eng Online. 2019 Mar 12;18(1):22. doi: 10.1186/s12938-019-0641-6.

Abstract

Background: The resources of ultrafast technology can be used to add another analysis to ultrasound imaging: assessment of tissue viscoelasticity. Ultrafast image formation can be utilized to find transitory shear waves propagating in soft tissue, which permits quantification of the mechanical properties of the tissue via elastography. This technique permits simple and noninvasive diagnosis and monitoring of disease.

Methods: This article presents a method to estimate the viscoelastic properties and rigidity of structures using the ultrasound technique known as shear wave elasticity imaging (SWEI). The Verasonics Vantage 128 research platform and L11-4v transducer were used to acquire radio frequency signals from a model 049A elastography phantom (CIRS, USA), with subsequent processing and analysis in MATLAB.

Results: The images and indexes obtained reflect the qualitative measurements of the different regions of inclusions in the phantom and the respective alterations in the viscoelastic properties of distinct areas. Comparison of the results obtained with this proposed technique and other commonly used techniques demonstrates the characteristics of median filtering in smoothing variations in velocity to form elastographic images. The results from the technique proposed in this study are within the margins of error indicated by the phantom manufacturer for each type of inclusion; for the phantom base and for type I, II, III, and IV inclusions, respectively, in kPa and percentage errors, these are 25 (24.0%), 8 (37.5%), 14 (28.6%), 45 (17.8%), and 80 (15.0%). The values obtained using the method proposed in this study and mean percentage errors were 29.18 (- 16.7%), 10.26 (- 28.2%), 15.64 (- 11.7%), 45.81 (- 1.8%), and 85.21 (- 6.5%), respectively.

Conclusions: The new technique to obtain images uses a distinct filtering function which considers the mean velocity in the region around each pixel, in turn allowing adjustments according to the characteristics of the phantom inclusions within the ultrasound and optimizing the resulting elastographic images.

Keywords: Elastography; Shear wave; Signal processing; Ultrafast imaging; Ultrasound.

MeSH terms

  • Algorithms
  • Elasticity Imaging Techniques*
  • Image Processing, Computer-Assisted / methods*
  • Phantoms, Imaging
  • Time Factors