Hypokalemia can cause abnormalities in multiple systems. Long term use of antipsychotic medications can lead to electrolyte imbalance, including hypokalemia. We report a 49-year-old female patient with schizophrenia who developed hypokalemia after oral quetiapine and risperidone treatments. Her blood potassium became normal after she switched to another antipsychotic drug (amisulpride). In addition, we discuss the potential mechanism of antipsychotic drugs leading to hypokalemia and clinical cautions.
低血钾可造成躯体多系统障碍，长期服用某些 抗精神病药可能会导致电解质代谢的异常，包括血清 钾的异常。我们报告一例49 岁女性精神分裂症患者， 在服用奎硫平和利培酮后出现低血钾，在换用其它抗 精神病药（氨磺必利）后，血钾恢复正常。我们还讨 论了抗精神病药导致低血钾的可能机制和临床注意事 项。.
Keywords: Hypokalemia; antipsychotic drugs; quetiapine; risperidone; schizophrenia; somatic.