Simple Analysis of the Computed Tomography Features of Gastric Schwannoma

Jian Wang; Wenming Zhang; Xiaoxuan Zhou; Junliang Xu; Hong-Jie Hu

doi:10.1016/j.carj.2018.09.002

Simple Analysis of the Computed Tomography Features of Gastric Schwannoma

Can Assoc Radiol J. 2019 Aug;70(3):246-253. doi: 10.1016/j.carj.2018.09.002. Epub 2019 Mar 8.

Authors

Jian Wang¹, Wenming Zhang², Xiaoxuan Zhou², Junliang Xu³, Hong-Jie Hu⁴

Affiliations

¹ Department of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, China.
² Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, Zhejiang Province, China.
³ Department of Radiology, Jianggan District People's Hospital, Hangzhou, Zhejiang Province, China.
⁴ Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, Zhejiang Province, China. Electronic address: hongjiehu@zju.edu.cn.

PMID: 30853303
DOI: 10.1016/j.carj.2018.09.002

Abstract

Objective: The objective of this study was to assess the computed tomography (CT) findings of gastric schwannoma (GS) and identify the difference between large (> 5 cm) and small (≤ 5 cm) GS.

Materials and methods: CT findings of 38 pathologically proven cases of GSs were retrospectively reviewed. The CT evaluation of GS included categorical variables (location, contour, growth pattern, enhancement pattern, necrosis, ulceration, calcification, and lymph nodes) and continuous variables (size, CT value of 3 phases, and enhancement degree). The lesion was divided into 2 groups (large [> 5 cm] and small [≤ 5 cm] GS) according to the tumor size. The Fisher exact test was used for categorical variables and the Student t or Mann-Whitney U test for continuous variables.

Results: Of the 38 patients, there were 32 women and 6 men. The median age was 54.5 years (range 39-79). Most of patients (65.8%, [25 of 38]) had nonspecific gastrointestinal symptoms such as abdominal or gastric pain, fullness and discomfort, bleeding, and melena. The tumors were mainly located in the stomach body (71.1% [27 of 38]), and the mean diameter was 3.7 cm (range 1.5 cm-10.3 cm), of which included large (> 5 cm) (n = 8) and small (≤ 5 cm) (n = 30). All of the GSs were benign, 9 of whom had palpable perigastric lymph nodes, which confirmed by pathology for the reactive inflammatory hyperplasia. Growth pattern, pattern of enhancement, necrosis, calcification, surface ulceration, and lymph node in the CT images were found to be significant variables for differentiating large (> 5 cm) and small (≤ 5 cm) GS (P < .05).

Conclusion: GSs were predominantly located at the gastric body and occurred most frequently in women between the ages of 40-70 years, and showed gradual enhancement after contrast enhancement. Palpable perigastric lymph nodes could not be considered as malignant factor of GS. There 7 computed CT criteria are significant difference between large (> 5 cm) and small (≤ 5 cm) GS.

Keywords: Gastric neoplasm; Schwannoma; X-ray computed tomography.

MeSH terms

Adult
Aged
Female
Humans
Image Interpretation, Computer-Assisted / methods*
Male
Middle Aged
Neurilemmoma / diagnostic imaging*
Retrospective Studies
Stomach / diagnostic imaging
Stomach Neoplasms / diagnostic imaging*
Tomography, X-Ray Computed / methods*