We assessed the utility of near-infrared spectroscopy to evaluate neonates with mitochondrial disorders. We observed abnormally high cerebral oxygen saturation levels indicating insufficient tissue oxygen utilization. We propose that near-infrared spectroscopy may be an additional tool in the diagnostic evaluation of a suspected mitochondrial disorder.
Keywords: NIRS; lactic acidosis; mitochondrial; respiratory chain; spectroscopy.
Copyright © 2019 Elsevier Inc. All rights reserved.