Necrotizing pneumonia (aetiology, clinical features and management)

Curr Opin Pulm Med. 2019 May;25(3):225-232. doi: 10.1097/MCP.0000000000000571.

Abstract

Purpose of review: Necrotizing pneumonia is a severe form of community-acquired pneumonia characterized by rapid progression of consolidation to necrosis and cavitation which may lead to pulmonary gangrene. Morbidity and mortality are high and chronic sequelae are frequent. The lack of guidance supports the review of the latest recommendations in the management of these pneumonias.

Recent findings: Antibiotic therapy alone may not be enough to alter the course of the infection, and regimens, adjunctive therapies like intravenous immunoglobulins, surgery may be required to alter the course of the disease especially with pulmonary gangrene.

Summary: The causative agents, clinical features and management of necrotizing pneumonias are discussed.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Community-Acquired Infections / diagnostic imaging
  • Community-Acquired Infections / microbiology
  • Community-Acquired Infections / therapy
  • Humans
  • Pneumonia, Necrotizing / diagnostic imaging
  • Pneumonia, Necrotizing / microbiology*
  • Pneumonia, Necrotizing / therapy*

Substances

  • Anti-Bacterial Agents