Chondrosarcoma

Excerpt

Chondrosarcomas are malignant cartilaginous neoplasms with diverse morphological features and clinical behavior. They account for about 20% of all primary malignant tumors of the bone . They usually arise in the pelvis or long bones . Primary or conventional chondrosarcoma arises in preexisting normal bone and is distinguished from the rarer secondary tumors, which occur in a preexisting enchondroma or osteochondroma . Conventional chondrosarcoma, which accounts for 85%–90% of chondrosarcomas is subdivided into the central, periosteal, and peripheral subgroups . Non-conventional chondrosarcoma variants include clear cell chondrosarcoma, mesenchymal chondrosarcoma, and dedifferentiated chondrosarcoma . The radiographic features of chondrosarcoma are often very characteristic, and a definitive diagnosis can usually be made by imaging examination alone.