Maturational changes in vancomycin protein binding affect vancomycin dosing in neonates

Br J Clin Pharmacol. 2019 May;85(5):865-867. doi: 10.1111/bcp.13899. Epub 2019 Mar 4.

Stéphanie Leroux^{1

2}, Johannes N van den Anker^{1

3}, Anne Smits^{4

5}, Marc Pfister^{1

6}, Karel Allegaert^{5

7}

¹ Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel, University of Basel, Basel, Switzerland.
² Neonatal Intensive Care Unit, University Hospital Rennes, Rennes, France.
³ Division of Clinical Pharmacology, Children's National Health System, Washington, DC, USA.
⁴ Neonatal Intensive Care Unit, University Hospitals Leuven, Leuven, Belgium.
⁵ Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
⁶ Certara LP, Princeton, NJ, USA.
⁷ Department of Pediatrics, Division of Neonatology, Erasmus MC Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, The Netherlands.

No abstract available

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