Helicopter noise exhibits distinctive acoustical characteristics (e.g., pulsation) compared to noise from propeller-driven aircraft which contains tonal components. Whereas, at comparable sound exposure levels (LAE), annoyance reactions to these sources might be different, knowledge of potential annoyance differences is scarce. This paper reports a comparison between short-term annoyance reactions to noise from light-weight helicopters and propeller-driven aircraft in a laboratory setup. Stimuli were presented with a 3D sound reproduction system in a listening test facility based on field recordings of takeoffs and landings. Propagation filtering and amplitude changes were carried out to simulate various propagation distances and source levels, covering a reasonable LAE range from 64 to 85 dB(A) for a stimuli length of 24 s. Fifty-six subjects rated their short-term annoyance reactions on the ICBEN 11-point numerical scale. Associations between design variables (source type, procedure, and LAE) and short-term annoyance were explored by means of a linear mixed-effect model. LAE was found to be the major predictor. For the major range of LAE, no significant difference was found between annoyance to noise from the two aircraft types. Observed level differences at equal annoyance ratings were below 1 dB. Furthermore, helicopter landings were found slightly more annoying than helicopter takeoffs.