Description of Klebsiella africanensis sp. nov., Klebsiella variicola subsp. tropicalensis subsp. nov. and Klebsiella variicola subsp. variicola subsp. nov

Carla Rodrigues; Virginie Passet; Andriniaina Rakotondrasoa; Thierno Abdoulaye Diallo; Alexis Criscuolo; Sylvain Brisse

doi:10.1016/j.resmic.2019.02.003

Description of Klebsiella africanensis sp. nov., Klebsiella variicola subsp. tropicalensis subsp. nov. and Klebsiella variicola subsp. variicola subsp. nov

Res Microbiol. 2019 Apr-May;170(3):165-170. doi: 10.1016/j.resmic.2019.02.003. Epub 2019 Feb 25.

Authors

Carla Rodrigues¹, Virginie Passet², Andriniaina Rakotondrasoa³, Thierno Abdoulaye Diallo⁴, Alexis Criscuolo⁵, Sylvain Brisse⁶

Affiliations

¹ Biodiversity and Epidemiology of Bacterial Pathogens, Institut Pasteur, Paris, France. Electronic address: carla.parada-rodrigues@pasteur.fr.
² Biodiversity and Epidemiology of Bacterial Pathogens, Institut Pasteur, Paris, France. Electronic address: virginie.passet@pasteur.fr.
³ Institut Pasteur Madagascar, Antananarivo, Madagascar. Electronic address: aina@pasteur.mg.
⁴ Institut Pasteur Dakar, Dakar, Senegal. Electronic address: Thierno.Diallo@pasteur.sn.
⁵ Hub de Bioinformatique et Biostatistique - C3BI, Institut Pasteur, USR 3756, CNRS, Paris, France. Electronic address: alexis.criscuolo@pasteur.fr.
⁶ Biodiversity and Epidemiology of Bacterial Pathogens, Institut Pasteur, Paris, France. Electronic address: sylvain.brisse@pasteur.fr.

PMID: 30817987
DOI: 10.1016/j.resmic.2019.02.003

Abstract

The bacterial pathogen Klebsiella pneumoniae comprises several phylogenetic groups (Kp1 to Kp7), two of which (Kp5 and Kp7) have no taxonomic status. Here we show that group Kp5 is closely related to Klebsiella variicola (Kp3), with an average nucleotide identity (ANI) of 96.4%, and that group Kp7 has an ANI of 94.7% with Kp1 (K. pneumoniae sensu stricto). Biochemical characteristics and chromosomal beta-lactamase genes also distinguish groups Kp5 and Kp7 from other Klebsiella taxa. We propose the names Klebsiella africanensis for Kp7 (type strain, 200023^T = CIP 111653^T) and K. variicola subsp. tropicalensis for Kp5 (type strain, 1266^T = CIP 111654^T).

Keywords: Beta-lactamase; Genome sequencing; Human carriage; Klebsiella pneumoniae complex; Phylogeny; Taxonomy.

MeSH terms

Bacterial Typing Techniques*
Klebsiella / classification*
Klebsiella / enzymology
Klebsiella / genetics
Klebsiella / physiology
Phylogeny*
Sequence Homology
beta-Lactamases / genetics

Substances

beta-Lactamases