Towards a Non-Invasive Technique for Healing Assessment of Internally Fixated Femur

Sensors (Basel). 2019 Feb 19;19(4):857. doi: 10.3390/s19040857.

Abstract

The lack of a quantitative method to adequately assess fractured bone healing that has undergone fixation limits prognostic capabilities on patients' optimal return to work. This paper addresses the use of vibrational analysis to monitor the state of healing of a plate-screw fixated femur and supplement the current clinical radiographic assessment. This experimental study involves an osteotomised composite femur specimen enclosed by modelling clay to simulate the damping effect of overlying soft tissues. Epoxy adhesives are applied to the fractured region and to simulate the healing process. With the instrumentation described, the cross-spectrum and coherence are obtained and analysed in the frequency domain over a period of time. The results suggest that it is crucial to analyse the cross-spectrum and proposed healing index to quantitatively assess the stages of healing. The results also show that the mass loading effect due to modelling clay did not influence the proposed healing assessment technique. The findings indicate a potential non-intrusive technique to evaluate the healing of fractured femur by utilising the vibrational responses.

Keywords: dynamic response; fractured femur; healing assessment; internal fixation; spectral analysis.

MeSH terms

  • Biomechanical Phenomena
  • Bone Plates
  • Bone Screws
  • Cadaver
  • Epoxy Compounds / administration & dosage*
  • Femoral Fractures / drug therapy*
  • Femoral Fractures / physiopathology
  • Femoral Fractures / surgery
  • Femur / drug effects*
  • Femur / physiopathology
  • Finite Element Analysis
  • Humans
  • Internal Fixators
  • Wound Healing*

Substances

  • Epoxy Compounds