Twelve weeks of exercise modality in hypoxia enhances health-related function in obese older Korean men: A randomized controlled trial

Geriatr Gerontol Int. 2019 Apr;19(4):311-316. doi: 10.1111/ggi.13625. Epub 2019 Feb 20.

Abstract

Aim: The aim of the present study was to examine the effect of exercise intervention in hypoxia as a novel treatment method for obesity in older men.

Methods: A total of 24 obese 65-70-year-old Korean men (66.5 ± 0.8 years) were randomly assigned to undergo hypoxic training (n = 12) or normoxic training (n = 12), and all participants carried out an exercise intervention composed of aerobic exercise on a treadmill (30 min) and bicycle (30 min), and resistance exercise (30-40 min) in normoxia, and 3000-m normobaric hypoxia separately for a total of 12 weeks, three times a week. Health-related dependent variables (body composition, physical fitness, pulmonary function and heart rate variability) were evaluated at pre- and post-exercise intervention.

Results: Hypoxic training showed more improved body composition (bodyweight -5.68 vs -3.16 kg, %body fat -5.50 vs -1.97%, fat-free mass 2.09 vs 1.06 kg), physical fitness (chair sit-to-stand 5.67 vs 4.58, pegboard 3.58 vs 2.17, tandem test -1.74 vs -1.31 s, one leg standing 6.27 vs 3.71 s), pulmonary function (forced vital capacity 0.15 vs 0.02 L, forced expiratory volume in 1 s 0.23 vs 0.01 L, percent of forced expiratory volume in 1 s 0.87 vs 0.08, maximal voluntary ventilation 5.26 vs 2.22 L) and heart rate variability (high frequency 0.94 vs 0.19 ms2 , low frequency/high frequency -0.28 vs -0.08, salivary cortisol -0.13 vs -0.04 μg/dL) than normoxic training.

Conclusions: Compared with normoxic training, hypoxic training is a novel and successful health promotion method in obese older populations. Geriatr Gerontol Int 2019; 19: 311-316.

Keywords: body composition; heart rate variability; hypoxic training; physical fitness; pulmonary function.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Body Mass Index
  • Exercise / physiology*
  • Exercise Test / methods
  • Female
  • Humans
  • Hypoxia* / etiology
  • Hypoxia* / prevention & control
  • Male
  • Obesity* / diagnosis
  • Obesity* / physiopathology
  • Obesity* / therapy
  • Oxygen Consumption
  • Physical Fitness / physiology*
  • Resistance Training / methods*
  • Treatment Outcome