Applying activated carbon (AC) to contaminated sediments is an in-situ approach to remediation with great potential. The bioavailability of persistent organic pollutants can be rapidly reduced and kept low over long periods of time. However, there are limitations to the method. The high buoyancy of AC particles makes their application difficult in the field, and AC retention on the amended site can be low in turbulent waters. Furthermore, the fine particles of powdered AC (PAC) can have adverse effects on organisms, but their remediation potential is superior to coarser, granular ACs (GAC). To tackle these shortcomings, a novel sorbent material was developed, consisting of PAC embedded into a stable, granular clay-matrix, significantly reducing buoyancy. These AC-clay granules (ACC-G) were tested for remediation potential (PCB-bioaccumulation reduction) and adverse effects on the benthic invertebrates Chironomus riparius and Lumbriculus variegatus. The novel ACC-G material was compared to GAC of the same particle size, the clay-matrix, and PAC. The findings show that ACC-G has a significantly higher remediation potential than GAC, allowing for reductions in PCB-bioaccumulation of up to 89%. Adverse effects could not be totally eliminated with ACC-G, but they were less severe than with PAC, likely due to the increased particle size.