A New Vascular Engineering Strategy Using 3D Printed Ice

Trends Biotechnol. 2019 May;37(5):451-453. doi: 10.1016/j.tibtech.2019.01.007. Epub 2019 Feb 14.

Abstract

Vascular engineering requires integrating dimensional flexibility, strength, and bioactivity to fabricate materials that enable diffusive exchange of oxygen and nutrients between cells and their environment. A recent publication (Biomaterials 2019;192:334-345) has described a new method of creating freestanding, tailorable, and biocompatible vascular constructs by coating ice scaffolds with natural or synthetic polymers.

Keywords: dimensional flexibility; ice scaffolds; tropoelastin; vascular constructs; vascular engineering.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials
  • Blood Vessels* / cytology
  • Blood Vessels* / physiology
  • Cells, Cultured
  • Humans
  • Ice*
  • Printing, Three-Dimensional*
  • Tissue Engineering*
  • Tissue Scaffolds

Substances

  • Biocompatible Materials
  • Ice