The optimal revascularization strategy for CAD in the TAVR population is not well-defined and decisions about which patients require PCI have been largely operator dependent or based on SYNTAX score. In a TAVR population, complete revascularization does not improve short or long term mortality, but is associated with decreased acute myocardial infarction and revascularization, when compared with incomplete revascularization. Future prospective studies should evaluate revascularization strategies in TAVR patients, including considering functional lesion assessment with fractional flow reserve, especially as TAVR indications are likely to soon expand to a younger and healthier cohort.
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