Leukocytoclastic vasculitis secondary to clozapine

Indian J Psychiatry. 2019 Jan-Feb;61(1):94-96. doi: 10.4103/psychiatry.IndianJPsychiatry_384_18.

Abstract

Leukocytoclastic vasculitis (LCV) may be secondary to drugs, underlying infection, collagen vascular disorders, or malignancy. Drug-induced vasculitis contributes to 10% of vasculitic skin lesions cases usually developing within 7-21 days of treatment initiation. The present case highlights a report of LCV in a 59-year-old male with a history of paranoid schizophrenia on clozapine therapy. The report upsurges the need to promote awareness and expedite diagnosis and treatment of drug-induced LCVs.

Keywords: Clozapine; leukocytoclastic vasculitis; pharmacovigilance.

Publication types

  • Case Reports